Antioxidants, Free radicals, Body health, Oxidation reactions, Field use, Excess;
Although initial
studies suggested that antioxidant supplements might promote health, later
large clinical trials with a limited number of antioxidants detected no benefit
and even suggested that excess supplementation with certain putative
antioxidants may be harmful.
Oxidative stress disadvantages;
What is an antioxidant?
An
antioxidant is a molecule that inhibits the oxidation of other molecules.
Oxidation is a chemical reaction that transfers electrons or hydrogen from a
substance to an oxidizing agent.
Free radicals harmful:
Oxidation
reactions can produce free radicals. In turn, these free radicals can start
chain reactions. When the chain reaction occurs in a cell, it can cause damage
or death to the cell.
Antioxidants role in the body health:
Antioxidants
terminate chain reactions by removing free radical intermediates, and inhibit other
oxidation reactions. They do this by being oxidized themselves; therefore
antioxidants are often reducing agents such as thiols, ascorbic acid, or
polyphenols.
Oxidation reactions drawbacks:
Although
oxidation reactions are crucial for life, they can also be damaging factors;
plants and animals maintain complex systems of multiple types of antioxidants,
such as glutathione, vitamin C, vitamin A, vitamin E,
as well as enzymes like catalase, superoxide dismutase, and various peroxides.
Oxidative stress nuisance:
Insufficient
levels of antioxidants, or inhibition of the antioxidant enzymes, cause
oxidative stress and may damage or kill cells. Oxidative stress is damage to
cell structure and cell function by overly reactive oxygen containing molecules
and chronic excessive inflammation. Oxidative stress seems to play a
significant role in many human diseases, including cancers.
The use of antioxidants in pharmacology is intensively studied, particularly as
treatments for stroke and neurodegenerative diseases. For these reactions,
oxidative stress can be considered to be both the cause and the consequence of
some diseases.
Antioxidant fields use:
Antioxidants
are widely used in dietary supplements and have been investigated for the
prevention of diseases such as cancer, coronary heart disease and even altitude
sickness. Antioxidants also have many industrial uses, such as preservative in
food and cosmetics and to prevent the degradation of rubber and used to inhibit
gum formation in gasoline.
Antioxidant excess supplementation:
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